Five Prescription Drugs That Can Make Coping with Heat Harder

Learn about five common prescription drugs that can interfere with your body's ability to regulate temperature, making it challenging to stay cool in hot weather. From antidepressants to heart medications, discover how these drugs can impact sweating, blood flow, and fluid balance, increasing the risk of heat-related illness.

Jun 26, 2025 - 21:01
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As temperatures rise, the risk of heat-related illness increases, especially for individuals taking certain prescription drugs. These drugs can interfere with the body's temperature regulation mechanisms, making it challenging to stay cool. Here are some prescription drugs to be aware of during the summer:

1. Antidepressants: Selective serotonin reuptake inhibitors (SSRIs) and tricyclics (TCAs) may cause heat intolerance by affecting the body's ability to sweat. They can disrupt neurotransmitter levels in the brain, impacting sweating and body temperature regulation.

2. Antipsychotics: These drugs, by blocking dopamine and affecting serotonin levels, can disrupt the body's ability to sense and respond to temperature changes, leading to reduced sweating and difficulty cooling down.

3. Heart medications: Beta-blockers and diuretics can limit blood flow to the skin, reduce sweating, and increase the risk of dehydration during hot weather.

4. Stimulants: Drugs like amphetamines used for ADHD can raise body temperature, affect sweating, and potentially lead to dehydration or heatstroke, especially during exercise or in hot conditions.

5. Insulin: Warm temperatures can accelerate insulin absorption, causing low blood sugar levels, which may result in symptoms like dizziness, shaking, and sweating. Insulin should be stored properly to maintain its effectiveness.

It is important for individuals, especially older adults and those with chronic conditions, to take precautions when exposed to heat while on these medications. Staying hydrated, avoiding peak heat hours, and being aware of warning signs of heat-related illness are crucial steps to stay safe.

According to the source: The Conversation.

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