New Method Developed to Compare Alzheimer's Research Findings

Irish researchers have created a unique method to compare research results on potential Alzheimer's treatments, aiming to speed up the process of bringing new therapies to patients. The method, developed by scientists at Trinity College Dublin, allows for better comparison of data from international clinical trials, potentially leading to faster access to emerging treatments.

Jun 24, 2025 - 10:47
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New Method Developed to Compare Alzheimer's Research Findings

New method aims to bring novel Alzheimer’s treatments to patients sooner

Irish researchers have developed a mapping model that can compare results from multiple Alzheimer’s studies, aiming to improve outcomes for patients with the disease.

The research, led by scientists from Trinity College Dublin, seeks to compare findings from international clinical trials to expedite the availability of emerging therapies for patients.

Published in the journal Alzheimer’s & Dementia, the research maps the Mini-Mental State Examination (MMSE) and the Clinical Dementia Rating – Sum of Boxes (CDR-SB), allowing for translation of scores between these assessments.

The model, developed using data from 26,729 patients in the US National Alzheimer’s Coordinating Centres database, shows strong performance, particularly in early disease stages.

This mapping can support randomised controlled trials, enhance feasibility assessments, and standardise evidence submitted for health technology assessments across markets.

The study findings will aid regulators in comparing data to determine the approval of new Alzheimer’s treatments.

According to the source: Irish Medical Times.

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