3 Essential Lab Tests to Assess Cardiovascular Risk

Cardiovascular disease is on the rise globally. Dr. Jeremy London recommends LDL-C, ApoB, and Lp-a tests to evaluate heart health. Lifestyle changes can help manage LDL-C and ApoB, while Lp-a may require targeted medications. Regular screenings and healthy habits are crucial for preventing heart issues.

Jul 21, 2025 - 20:46
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3 Essential Lab Tests to Assess Cardiovascular Risk

Cardiovascular disease is on the rise, emphasizing the importance of early detection. Dr. Jeremy London recommends three key lab tests: LDL-C, ApoB, and Lp-a, to assess cardiovascular risk. Lifestyle changes can manage LDL-C and ApoB, while Lp-a, being genetically determined, requires controlling other risk factors and exploring targeted medications. Regular screenings and a healthy lifestyle are crucial for heart health.

LDL-C

ApoB

Lp-a

What should you do?

From young people dying suddenly of heart attacks to a 50% surge in cardiac medication sales in India over the past five years, cardiovascular disease (CVD) is clearly on the rise. Early detection can reduce the risk of cardiovascular disease, a leading cause of death worldwide. Dr. Jeremy London recommends three essential lab tests to evaluate cardiovascular risk. The first test is LDL-C, known as 'bad cholesterol,' a standard measure of the bad cholesterol that contributes to cardiovascular disease. Elevated LDL-C levels hint at cardiovascular disease by causing plaque buildup in arteries, leading to heart attacks and strokes.

The ApoB test provides a comprehensive view of cardiovascular risk by measuring atherogenic particles. This protein attaches to negative types of cholesterol that cause plaque buildup in blood vessels. A high ApoB count signals increased risk, even if LDL-C levels appear normal.

The third test is Lp-a, a genetically determined lipoprotein that significantly elevates the risk of heart attack and stroke when levels are high. Lp-a attaches to cholesterol particles and increases clotting risk. Lifestyle changes do not lower Lp-a, but controlling LDL-C and ApoB can decrease overall cardiovascular risk. Medications targeted to Lp-a are in current clinical trials.

If you have a family history of heart disease or experience symptoms like shortness of breath, fatigue, or chest discomfort, consult a doctor for a comprehensive heart health assessment. Prevention through regular screenings, a balanced diet, physical activity, and stress management is key to maintaining a healthy heart.

According to the source: Times of India.

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